In the popup window, check the Enabled box, then Apply, and OK.Look for the setting Turn off Microsoft Defender Antivirus in the right pane.Scroll down to Microsoft Defender Antivirus.In the app’s window on the left pane, find Computer Configuration and select the Administrative Templates, then Windows Components.From the taskbar, press the search icon to enter a search for Edit group policy, then click the result to run the Group Policy editor.Use the x in the top right to close the window. In the Tamper Protection section, a message will display stating that your device may be vulnerable.Choose Yes to confirm the Do you want to allow this app to make changes to your device? prompt.Scroll down to the Tamper Protection option, and toggle the slider to Off.Under Virus & threat protection settings, click on Manage settings.Choose Privacy & security, Windows Security, then Virus & threat protection.The first way to disable Defender is by using the Group Policy security tool. Disable Microsoft Defender Using Group Policy Settings